These run from the corners of the nose to the corners of the mouth and are a sure sign of aging.  They are never seen in young people.  They often occur in combination with hollowing beneath the eyes and lines/folds from the corners of the mouth downwards (melomental folds).

These lines/folds are easily and effectively treated with tissue augmentation filler injections.  They are one of the first areas tackled by beginners but a really professional looking outcome requires years of experience.  For example, combined treatment of the cheek prominence (Malar eminence) and eye hollows is required for the best outcome, a subtlety usually unappreciated by beginners.  Choose your Aesthetic Physician well.